The true arrival of Derrick Henry has been long anticipated, but DeMarco Murray has proven a major obstacle. There's no such issue this week.
With last week's back injury a non-issue, Keenan Allen is set to produce against a Jets defense that hasn't defended the slot well.
Nick Foles is a significant downgrade from Carson Wentz, but perhaps not all is lost for Philadelphia. Foles' last starting season was under Jeff Fisher, who held back Sam Bradford, Jared Goff, and Case Keenum.
If there was a week to start Tom Savage, this would be the one.
Leonard Fournette disappointed against the Cardinals last week, but with week of full practices the rookie should bounce back against the Colts.
Sammy Watkins hasn't done much for his new team in 2017, but he might be in position to start making up for lost time with teammate Robert Woods and Saints corner Marshon Lattimore out.
With Tyron Smith out again, Dak Prescott may face a fierce pass rush for the second week in a row as the Eagles head south.
Orleans Darkwa isn't the flashiest name in a week where Le'Veon Bell, Leonard Fournette, Carlos Hyde and others have great matchups, but the emerging runner gets a nice projection against the 49ers.
Along with the Saints vs. Buccaneers, the showdown between the Cowboys and Chiefs figures to be a high-scoring affair.
Deshaun Watson has been incredible for Houston recently, but a uniquely difficult test is ahead as he heads to Seattle.
Against a 49ers defense allowing 70.8 plays per game, Ezekiel Elliott is in position for his biggest game of the year.
After a month of letdowns with Julio Jones, the freak receiver is due to make up for lost time.
For the Seahawks to get past a surging Rams squad, they may need a big game from Jimmy Graham.
With Julio Jones lagging in the first three weeks, it's time for a correction in Week 4. Buffalo is too small and slow to keep up.
After a slow first two weeks in Washington, Terrelle Pryor is in position for a big game against his former team.