Jamaal Williams hasn't done much for the Saints this year but may now be forced into a huge role Week 18 against the Falcons.
Khalil Herbert re-emerged as Chicago's lead runner Week 16 and went over 100 yards, but his role moving forward may (or may not) depend on D'Onta Foreman's availability.
Ty Chandler's impressive Week 15 performance could keep him in the lead role even if Alexander Mattison returns from an ankle injury soon.
Five starting RBs left Week 13 contests early, potentially setting up lead roles for Ezekiel Elliott, Kenneth Gainwell and others. Meanwhile, Chuba Hubbard and James Conner topped 100 yards and scored twice.
Roschon Johnson took over the lead role Monday night, but it's unclear if that will hold after a Week 13 bye.
Juan Carlos Blanco examines the latest news on the Week 12 injury report as of early Sunday, including updates on a large contingent of ailing wide receivers.
AJ Dillon struggled in a lead role earlier this season, but he's played better recently and now gets another chance to replace an injured Aaron Jones as Green Bay's starting running back.
Juan Carlos Blanco surveys the extremely busy Week 11 Sunday morning injury landscape and dishes the latest news on the potential availability of multiple big fantasy names.
Devin Singletary's huge game in Cincinnati may have been enough to displace Dameon Pierce from the starting role once he returns from an ankle injury.
Steelers RB Jaylen Warren had a season-high for carries for the second straight week and topped 50 percent snap share for the first time all season.
Erik Siegrist previews the Monday night matchup as Russell Wilson and the Broncos travel to Buffalo for a date with the Bills.
Keaton Mitchell is a tough player to rank this week because of the Ravens' timeshare at RB and the tough opponent this week.
Zach Charbonnet took more snaps than Kenneth Walker again, and the Ravens introduced a lightning-fast rookie into their RB rotation.
Aaron Jones finally got back to a high-usage role after nearly two months of being held back by a hamstring injury.
Juan Carlos Blanco has the latest as of Sunday morning on a Week 9 injury report heavily populated by the quarterback position.
Sasha Yodashkin expects Derek Carr to have a solid day against the Bears this week. Check out all of his starts/sits for Week 9.